| Date | Location | Result | |
| 26.09.2010 | Langen | Langen Knights 29, Frankfurt Universe 28 | Box score |
| 10.07.2010 | Jena | Frankfurt Universe 45, Jena INJOY Hanfrieds 14 | Box score |
| 04.07.2010 | Frankfurt am Main | Frankfurt Pirates 41, Frankfurt Universe 18 | Box score |
| 26.06.2010 | Frankfurt am Main | Frankfurt Universe 27, RavensburgRazorbacks 8 | Box score |
| 05.06.2010 | Frankfurt am Main | Frankfurt Universe 54, Jena INJOY Hanfrieds 41 | Box score |
| 29.05.2010 | Freiburg | Freiburg Sacristans 17, Frankfurt Universe 9 | Box score |
| 22.05.2010 | Frankfurt am Main | Montabaur Fighting F 29, Frankfurt Universe 26 | Box score |
| 15.05.2010 | Frankfurt am Main | Frankfurt Pirates 41, Frankfurt Universe 20 | Box score |
| 08.05.2010 | Montabaur | Frankfurt Universe 41, Montabaur Fighting F 27 | Box score |
| 02.05.2010 | Frankfurt am Main | Frankfurt Universe 33, S Silver Arrows 9 | Box score |
| 25.04.2010 | Weingarten | Badener Greifs 35, Frankfurt Universe 34 | Box score |
| 18.04.2010 | Frankfurt am Main | Frankfurt Universe 19, Nuernberg Rams 7 | Box score |